• Mouse monoclonal antibody to BRCA1
• Application: ≥ WB, ELISA
• Species reactivity: Human
RING finger protein 53; RING-type E3 ubiquitin transferase BRCA1
Breast cancer type 1 susceptibility protein, BRCA1, is frequently mutated in inherited breast, ovarian cancer, as well as pancreatic cancer, Fanconi anemia, etc. It plays essential roles in DNA damage repair, cell cycle, transcription, ubiquitination, and apoptosis.